Yevgeny Yehudin was born into a musical family in the former Soviet Union. As a child, he studied both the piano and the clarinet in his hometown, Minsk, and subsequently graduated from the Minsk Music Academy. During his studies, he was twice the recipient of First Prize at the Belarusian National Competition.

In 1991, he immigrated to Israel and continued his studies at Tel Aviv University. In 1992, he joined the Israel Sinfonietta Beer Sheva as Principal Clarinet and later became the head of the wind section of the orchestra.

Yevgeny has appeared as a soloist with the Israel Philharmonic Orchestra under the baton of Maestro Zubin Mehta and with the Israel Sinfonietta Beer Sheva. He performs frequently as a chamber musician with renowned artists such as Yuri Bashmet, Nobuko Imai, Elena Bashkirova, Guy Braunstein, Gary Hoffman, Steven Kovacevic, the Ysaye String Quartet, and the Jerusalem String Quartet. He has appeared at the Jerusalem International Chamber Music Festival, the Gaia Chamber Music Festival in Thun, and at the Rolandseck Festival.

Yevgeny records frequently for radio stations both in Israel and abroad. He is a regular member of the Israel Woodwind Quintet and has recorded label CDs for the Israel Music Center, Meridian, and DUX. In 1994, he won the François Shapira Prize for young musicians. Yehudin serves as a clarinet teacher at the Hebrew University of Jerusalem and Tel Aviv University.

Yevgeny was appointed Principal Clarinet of the Israel Philharmonic Orchestra in 2002.